P0423Patient-Physician mismatch in therapeutic targets for advanced therapy in inflammatory bowel disease patients: the PROMISE study

Key Points

To explore the mismatch between therapeutic targets set by patients versus those set by physicians in advanced IBD therapies.
National observational study conducted in Italy
Involved IBD patients initiating advanced therapy
Patients and physicians independently selected and ranked therapeutic targets from a predefined list
Assessed target achievement at Weeks 26 and 52
67.7% of patients achieved their primary predefined target by Week 52
75.4% of patients achieved the physician's primary expected target at Week 52
Significant disparity in achieving three targets: 59.1% for physicians vs. 46.3% for patients
Patients in clinical remission had higher multi-target achievement rates (73.4%)

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Observational study explores target achievement discrepancies in IBD patients, suggesting the need for better alignment with patient goals.

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Fiorino et al. (2026) studied this question.

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