Biomimetic phage-inspired supramolecular system based on glucose-conjugated pillar5arene with ciprofloxacin hydrochloride

Key Points

• The central aim is to develop a self-assembling system inspired by phages to improve antibiotic effectiveness.
• Synthesis of glucose-conjugated pillar[5]arene carriers.
• Assessment of the system's water solubility.
• Evaluation of antimicrobial efficacy against resistant strains.
• The synthesized system showed enhanced water solubility compared to traditional carriers.
• Improved antimicrobial effects against antibiotic-resistant bacteria were observed.