Catalytic cycloaddition generates novel N-aminooxazol-2-one scaffolds from alkynes and azodicarboxylate, indicating a new synthetic route.
A regioselective (3+2) cycloaddition between terminal alkynes and di-tert butyl azodicarboxylate under catalytic conditions is reported for the synthesis of novel N-aminooxazol-2-one scaffolds. The reaction employs an in situ-generated copper...
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Lei et al. (2026) studied this question.
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