Optimizing the amino terminal Cu( ii )- and Ni( ii )-binding (ATCUN) motif for Cu( ii ) complexes with improved inertness

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Agents mobilizing cu(II) from the inert ATCUN complex need both high affinity and a specific chelating structureOriginal Research · 2026
2. 2Revisiting Significance of Kinetic Inertia in Complex formation/decomplexation of Metal-ATCUN Peptide Complex.2025
3. 3Structure-Activity Relationships of ATCUN-Based Cu(II) Complexes with Large Chelate Rings: Interplay of ROS Generation, DNA Binding, and Nuclease ActivityOriginal Research · 2026
4. 4Abstract 2055 "Mutating D111 in the Cu A protein to Determine the Reactivity of Ligating Histidines to Chemical Modifiers"2024
5. 5A ¹⁹F‐ATCUN Peptide NMR Probe for Selective Cu²⁺ or Ni²⁺ Sensing in Complex Biological Media2025