The Peptide Plastic Surgeon: A Review of Evidence on Regenerative Peptide Supplementation and Potential in Aesthetic Plastic Surgery

Regenerative peptides are gaining attention in regenerative medicine and plastic surgery for their potential to enhance surgical recovery and tissue regeneration. This review synthesizes evidence on four key peptides—focusing on their potential applications in wound healing, scar optimization, and aesthetic plastic surgery. Preclinical studies show promise, safety profiles appear favorable, but rigorous clinical trials are lacking. The paucity of human studies highlights an urgent need for high-quality research. Plastic surgeons are well-positioned to lead investigations, integrating regenerative peptides into perioperative care and evaluating their ability to optimize outcomes in aesthetic procedures.