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Experimental analysis reveals hormonal effects on astrocyte morphology in human cortical tissue, suggesting implications for CNS symptoms.
Estradiol, tamoxifen, and raloxifene - widely used hormonal agents - were associated with distinct effects on astrocyte morphology in human cortical tissue. These findings support a role for estrogen receptor modulation in astroglial structural regulation and suggest a potential cellular mechanism contributing to central nervous system symptoms reported in clinical settings.
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Silva et al. (2026) studied this question.
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