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January 1, 2026Polymer Chemistry

Glutathione-Responsive Degradable Amphiphilic Polyester-Based Nanocarrier for Targeted Drug Delivery

Ankita Banerjee Subhendu Biswas Anindita Das

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Key Points

The aim is to develop a nanocarrier that breaks down in the presence of glutathione to target cancer cells more effectively.
Synthesis of an amphiphilic polyester-based nanocarrier
Characterization of disulfide bond responsiveness to glutathione
In vitro tests to evaluate drug delivery capabilities in cancerous cells
The nanocarrier demonstrated enhanced drug release in the presence of glutathione
Targeted drug delivery was confirmed to be more effective in cancer cells compared to non-cancerous cells
Improved treatment outcomes were suggested based on preliminary observations of efficacy

Implication

Experimental development of a degradable nanocarrier enhances targeted drug delivery in cancer therapy, suggesting improved treatment efficacy.

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Cite This Study

Banerjee et al. (2026) studied this question.

synapsesocial.com/papers/6974616cbb9d90c67120b38e https://doi.org/10.1039/d5py01148e

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