Recent developments in the delivery of peptide nucleic acid (PNAs)

Srijani Sarkar; Niren Murthy

doi:10.1039/d5cb00301f

January 1, 2025RSC Chemical BiologyOpen Access

Recent developments in the delivery of peptide nucleic acid (PNAs)

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Key Points

The central focus is to explore new strategies for the effective delivery of peptide nucleic acids (PNAs) as therapeutics.
Review recent advancements in delivery strategies for PNAs.
Analyze the challenges associated with PNA delivery.
Discuss the implications of improved solubility for therapeutic applications.
New delivery strategies enhance the solubility of PNAs.
Potential improvements in therapeutic efficacy for various diseases.
Overcoming previous limitations in PNA development.

Implication

Recent advancements improve therapeutic delivery of peptide nucleic acids, indicating better clinical applications.

Abstract

Peptide nucleic acid (PNA) oligomers have tremendous potential as therapeutics; however, their delivery is challenging and has limited their development as therapeutics. In recent years, new strategies for delivering water-soluble...

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Cite This Study

Sarkar et al. (2025) studied this question.

synapsesocial.com/papers/697462b5244d6b1945963f34 https://doi.org/10.1039/d5cb00301f

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Recent developments in the delivery of peptide nucleic acid (PNAs)

Key Points

Implication

Abstract

Discussion

Cite This Study

Recent developments in the delivery of peptide nucleic acid (PNAs)

Key Points

Implication

Abstract

Discussion

Cite This Study

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