Bisphosphonate-Associated Ocular Adverse Events with an Emphasis on Uveitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Key Points

• To investigate the association between bisphosphonate use and ocular adverse events, focusing on uveitis.
• Conducted a systematic review and meta-analysis of randomized controlled trials.
• Examined ocular adverse events related to bisphosphonate use.
• Reported findings specific to the onset post-intravenous administration.
• Bisphosphonate use is linked to a significantly higher risk of ocular adverse events.
• The risk of developing uveitis is notably elevated during the first three days after intravenous administration.