This research demonstrates quantitative monitoring of mitochondrial pH dynamics in cells during metformin treatment, highlighting the probes' effectiveness.
Starvation Hypoxia Oxidative stressFly larvaeHighlights• Two ratiometric fluorescent probes, AH⁺ and BH⁺, were synthesized from IR-780 iodide, incorporating imidazole, hydroxy-xanthene, and hemicyanine groups for selective mitochondrial targeting.• The probes operate...
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Schwandt et al. (2026) studied this question.
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