This research shows the impact of histone deacetylation inhibitors on adipogenic differentiation in mesenchymal stem cells, suggesting an anti-obesity potential.
Taken together, the results show a possible anti-obesity effect of histone deacetylation inhibitors (HDCAs) in MSCs, resulting in depletion and restriction of their adipogenic differentiation.
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Chandramoorthy et al. (2026) studied this question.
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