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January 25, 2026PLoS ONEOpen Access

The effects of iTBS to cerebellar vermis on balance function in frail older people: A protocol for a randomized controlled trial

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Authors

ZLZuoyan LiuSichuan UniversityNHNeng HuangSichuan UniversityKZkehong Zhao

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Implication

Randomized controlled trial evaluates the impact of iTBS on balance function in frail older individuals, suggesting new rehabilitation strategies.

Key Points

  • To evaluate the efficacy of intermittent theta burst stimulation to cerebellar vermis on balance function in frail older people.
  • Double-blind, two-arm randomized controlled trial design
  • Recruitment of frail older adults with balance dysfunction
  • Random assignment to experimental (iTBS) and control groups at a 1:1 ratio
  • Daily motor training sessions for all participants
  • Assessment of primary and secondary outcomes pre- and post-intervention.
  • Anticipated improvement in balance function post-iTBS intervention
  • Expected positive changes in frailty and walking ability
  • Potential enhancements in sensory organization and stability limits.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6975b38dfeba4585c2d6f0a6https://doi.org/10.1371/journal.pone.0339030
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Measuring balance in the elderly: preliminary development of an instrument1989 · 2,775 citations
  2. 2Postural Control Strategies and Balance-Related Factors in Individuals with Traumatic Transtibial Amputations2021 · 16 citations
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  4. 4Effect of Kinesiology Tape on Muscle Activation of Lower Extremity and Ankle Kinesthesia in Individuals With Unilateral Chronic Ankle Instability2021 · 23 citations
  5. 5Frailty in Older Adults: Evidence for a Phenotype2001 · 25,236 citations