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January 26, 2026Scandinavian Journal of Medicine and Science in Sports2 citationsOpen Access

Low‐Load Blood Flow Restriction Training Enhances Brachial Blood Flow During Exercise but not Reactive Hyperemia in Experienced Climbers

TPTitouan P. PerrinHRHugo RandyPSPyrène Santal

Key Result

A 5-week low-load blood flow restriction training protocol significantly improved brachial blood flow during exercise (+19%; p=0.011, d=0.5) in male climbers compared to high-load or no training.

Key Points

  • The research aims to evaluate vascular adaptations resulting from low-load blood flow restriction training in climbers.
  • Conducted a 5-week training intervention with 12 male climbers in three groups: LLBFRT, HLRT, and control.
  • Utilized brachial doppler-ultrasound to measure blood flow and muscle oxygenation at varying contraction intensities.
  • Performed assessments before and after the training using flow-mediated dilation and peak reactive hyperemia.
  • Brachial blood flow improved significantly during low-intensity contractions in the LLBFRT group (+19%).
  • No significant changes in reactive hyperemia or flow-mediated dilation were observed in any group.
  • Oxy- and total hemoglobin concentrations decreased less during contractions after LLBFRT compared to the other groups.

Structured PICO

Does low-load blood flow restriction training improve brachial blood flow and vascular adaptations compared to high-load resistance training or no training in male climbers?

P
Population
36 male climbers assigned to a 5-week finger flexor training protocol using low-load blood flow restriction, high-load resistance, or no training.
I
Intervention
5-week finger flexors protocol using low-load blood flow restriction training (LLBFRT) twice a week at ~40% of maximal voluntary contraction with cuff pressure at 60% of limb occlusion pressure
C
Comparator
High-load resistance training (HLRT) twice a week at ~75% of maximal voluntary contraction, and no specific training (CON)
O
Outcome
Flow-mediated dilation (FMD), peak reactive hyperemia blood flow, brachial blood flow, and muscle oxygenation at rest and during contractions from 10% to 60% MVCsurrogate

Low-load blood flow restriction training for 5 weeks improves brachial blood flow and oxygen availability during low-intensity contractions in male climbers, without altering macrovascular structure or endothelial function.

Main Result

Standardized Mean Difference: 0.5

p-value: p=0.011

Abstract

ABSTRACT Low‐load blood flow restriction training (LLBFRT) induces significant vascular stress, which is often associated with vascular remodeling, increased capillarization and muscle blood flow. These adaptations may be of interest to climbers as their endurance performance is limited by blood supply due to the isometric and intermittent nature of finger flexors (FD) contraction. This study, thus, aimed to assess vascular adaptations to a 5‐week FD protocol using LLBFRT ( n = 12, cuff pressure = 60% of the limb occlusion pressure) and compare these responses to those elicited by high‐load resistance training (HLRT, n = 12) and no specific training (CON, n = 12) in male climbers. Participants in LLBFRT and HLRT trained twice a week, respectively at ~40% and ~75% of maximal voluntary contraction (MVC). Before and after the intervention, flow‐mediated dilation (FMD), peak reactive hyperemia blood flow, brachial blood flow and muscle oxygenation (near‐infrared spectroscopy) at rest and during contractions from 10% to 60% MVC were assessed using brachial doppler‐ultrasound. Brachial blood flow across contraction intensities was significantly improved in LLBFRT (+19% ± 31%; p = 0.011, d = 0.5) but not in CON and HLRT. Oxy‐ and total hemoglobin concentrations decreased less during contraction following LLBFRT while did not change following CON and HLRT. Reactive hyperemia and FMD were not altered by any training modality. In conclusion, despite no difference with HLRT, LLBFRT was the only protocol which increased significantly blood flow of the feeding artery and O 2 availability during finger flexor low‐intensity contractions. However, these adaptations were not accompanied by modifications of macrovascular structure or endothelial function.

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Cite This Study

Perrin et al. (2026) studied Experienced climbers (n=36). Low-load blood flow restriction training (LLBFRT) vs. High-load resistance training (HLRT) and no specific training (CON) was evaluated on Brachial blood flow across contraction intensities (d = 0.5, p=0.011). A 5-week low-load blood flow restriction training protocol significantly improved brachial blood flow during exercise (+19%; p=0.011, d=0.5) in male climbers compared to high-load or no training.

synapsesocial.com/papers/69770353722626c4468e84c7https://doi.org/10.1111/sms.70211
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