The Overlooked Crisis: Drug Self-Intoxication Mortality Increased at 5 Times the Rate of Suicide Mortality During the US Opioid Epidemic (1999-2023)

Mushood Ahmed; Eeshal Zulfiqar; Aimen Shafiq; Maryam Shahzad; Tallal Mushtaq Hashmi; Faizan Ahmed; Raheel Ahmed; Namirah Jamshed

doi:10.1016/j.mayocp.2025.08.023

January 1, 2026Mayo Clinic ProceedingsOpen Access

The Overlooked Crisis: Drug Self-Intoxication Mortality Increased at 5 Times the Rate of Suicide Mortality During the US Opioid Epidemic (1999-2023)

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Implication

Analysis reveals drug self-intoxication death rates increased significantly more than suicide in individuals with substance use disorders, indicating a critical health crisis.

Abstract

Self-injury mortality among individuals with mental and behavioral disorders-especially those with substance use disorders-has steadily increased from 1999 to 2023. This rise has been driven primarily by a sharp increase in drug self-intoxication mortality, which has grown at over 5 times the rate of suicide mortality, alongside substantial demographic disparities.

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Cite This Study

Ahmed et al. (2026) studied this question.

synapsesocial.com/papers/697703af722626c4468e8c59 https://doi.org/10.1016/j.mayocp.2025.08.023

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The Overlooked Crisis: Drug Self-Intoxication Mortality Increased at 5 Times the Rate of Suicide Mortality During the US Opioid Epidemic (1999-2023)

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Implication

Abstract

Discussion

Cite This Study

The Overlooked Crisis: Drug Self-Intoxication Mortality Increased at 5 Times the Rate of Suicide Mortality During the US Opioid Epidemic (1999-2023)

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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