Key result
LVAA in ApHCM patients is linked to lower event-free survival and higher adverse event risk.
Why the study?
Does the presence of left ventricular apical aneurysm affect prognosis and CMR characteristics in patients with apical hypertrophic cardiomyopathy?
Population
1332 consecutive ApHCM patients confirmed by CMR
Comparison
ApHCM with LVAA vs age- and gender-matched ApHCM without LVAA
Design
Retrospective cohort study
Authors
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LVAA in ApHCM was associated with lower event-free survival; leaves open whether screening or intervention improves outcomes.
Does the presence of left ventricular apical aneurysm affect prognosis and CMR characteristics in patients with apical hypertrophic cardiomyopathy?
In patients with apical hypertrophic cardiomyopathy, left ventricular apical aneurysms are rare (2.3%), frequently missed by echocardiography, and associated with a worse prognosis.
Yang et al. (2020) studied this question. ApHCM patients with LVAA had a significantly lower event-free survival rate compared to those without LVAA (P = 0.010), indicating higher risk for adverse events.
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