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June 5, 2013Open Access

Abnormal Rich Club Organization and Functional Brain Dynamics in Schizophrenia

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Abstract

Our findings provide novel biological evidence that schizophrenia is characterized by a selective disruption of brain connectivity among central hub regions of the brain, potentially leading to reduced communication capacity and altered functional brain dynamics.

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Authors

Martijn P. van den Heuvel

Amsterdam Neuroscience

Olaf Sporns

Scripps Research Institute

Guusje Collin

Radboud University Nijmegen

Journals

JAMA Psychiatry

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Institutions

Indiana University Bloomington

University Medical Center Utrecht

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Heuvel et al. (Wed,) studied this question.

synapsesocial.com/papers/697cd1dca5c37a78ccb137ff — DOI: https://doi.org/10.1001/jamapsychiatry.2013.1328

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Estimating false positives and negatives in brain networks· 2013 · 292 citations
Undirected graphs of frequency-dependent functional connectivity in whole brain networks· 2005 · 443 citations
Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease· 2007 · 515 citations
Schizophrenia, neuroimaging and connectomics· 2012 · 748 citations
Disrupted Axonal Fiber Connectivity in Schizophrenia· 2010 · 449 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Estimating false positives and negatives in brain networks· 2013 · 292 citations
Undirected graphs of frequency-dependent functional connectivity in whole brain networks· 2005 · 443 citations
Diffusion tensor imaging of cingulum fibers in mild cognitive impairment and Alzheimer disease· 2007 · 515 citations
Schizophrenia, neuroimaging and connectomics· 2012 · 748 citations
Disrupted Axonal Fiber Connectivity in Schizophrenia· 2010 · 449 citations

Abnormal Rich Club Organization and Functional Brain Dynamics in Schizophrenia

Key Points

Abstract

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider