ABSTRACT Purpose Childhood empyema can have variable management and is associated with hospitalization and prolonged length of stay (LOS). We assessed the impact of a standard work pathway and associated electronic‐health record (EHR) order set on management and outcomes. Methods We conducted a single‐institution retrospective study of children hospitalized with empyema between 2015 and 2023. Pathway recommendations for antibiotics, consultations, MRSA screening, and pleural drainage before and after order set creation were compared using Chi‐squared or non‐parametric testing and over time by p‐charts. We used Cox proportional hazard models to assess association of pathway recommendations and outcomes (LOS, need for repeat procedures). We compared outcomes by race, ethnicity, and language using Mann‐Whitney and Kruskal‐Wallis tests. Results Of all 141 children in our cohort, 107 (76%) underwent pleural drainage, mostly chest tube with fibrinolytic ( n = 104). Pathway order set integration into the EHR was associated with a higher proportion of patients with Infectious Diseases consults and MRSA screens, but no difference in outcomes. In the whole cohort, 43 received first fibrinolytic ≥ 24 h after chest tube placement and 46.5% of these children required multiple procedures compared to those with timely fibrinolytic dose (15.6%, p = 0.0005). Median LOS was higher in children with non‐English language of care (LOC) ( p = 0.04). Of children needing pleural drainage, the proportion of multiple procedures differed by race/ethnicity ( p < 0.01) as well as LOC ( p = 0.03). Conclusions EHR integration of pathway‐based order set led to uptake of some recommended practices for management of pediatric empyema. Across the cohort, we identified opportunities to address gaps including an association between delayed fibrinolytic administration and higher rates of repeat procedures, and differences in LOS and repeat procedures by race/ethnicity and LOC. Clinical standard pathways integrated with informatics and quality improvement can be leveraged to prioritize equitable high‐quality care for children hospitalized with empyema.
Spurr et al. (Thu,) studied this question.