Multicomponent Reaction Strategies for the Synthesis of 4‐(Indol‐3‐Yl)‐4 H ‐Chromene Derivatives: Recent Developments

This review highlights recent advancements (2021–2025) in the synthesis of 4‐(indol‐3‐yl)‐4 H ‐chromene derivatives, a promising class of compounds with diverse biological activities, including anticancer, antifungal, antitumor, anti‐HIV, and antioxidant properties. The focus is on multicomponent reactions (MCRs) as a valuable tool for efficient synthesis, offering benefits such as environmental sustainability and precise targeting. The review explores MCR strategies and substrate scope, shedding light on their potential therapeutic applications.