Selective Deuteroreduction of Alkynes by Zn/Mn with Nickel Catalysis under Mechanical Conditions

Key Points

• The research aims to develop an efficient method for the selective deuteroreduction of alkynes using nickel catalysis.
• Utilized mechanochemical methods to facilitate the reaction.
• Applied zinc and manganese as reducing agents in the process.
• Examined the reaction conditions to avoid overreduction and incomplete conversion.
• Achieved selective deuteroreduction of alkynes avoiding overreduction issues.
• Demonstrated improved conversion rates compared to traditional methods.
• Reported successful tetra-deuteration under optimized mechanical conditions.