What question did this study set out to answer?

This study aims to compare the accuracy and acceptability of VISITECT CD4 versus PIMA CD4 testing in the advanced HIV disease care package.

Accuracy and acceptability of VISITECT CD4 Advanced Disease compared to PIMA CD4 at point-of-care as part of the AHD disease care package: A mixed methods study

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Mixed-methods study compares diagnostic accuracy and acceptability of VISITECT to PIMA among people with HIV.

This study aims to compare the accuracy and acceptability of VISITECT CD4 versus PIMA CD4 testing in the advanced HIV disease care package.
Conducted a mixed-methods study in a community-based TB case-finding trial in South Africa.
Compared VISITECT and PIMA tests using one venous blood sample from trial participants.
Calculated sensitivity, specificity, and predictive values for both tests.
Included in-depth interviews and focus groups with participants and nurses.
12.5% of participants had low CD4 counts on VISITECT compared to 4.8% on PIMA.
VISITECT showed sensitivity of 89.3% and specificity of 91.2%.
Low positive predictive value (32.9%) and high negative predictive value (99.4%) for VISITECT.
Nurses preferred PIMA due to accuracy, speed, and numeric results.

Gils et al. (2026) studied this question.

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