Key result
Endovascular repair reduces perioperative mortality and morbidity vs. open repair in anatomically suitable patients.
Endovascular therapy improves outcomes in aortic disease, suggesting wider treatment options for various conditions.
Endovascular therapy provides a new treatment modality for patients with aortic disease. By avoiding the morbidity of open surgery, endovascular approaches make treatment possible for a larger array of patients. However, the durability and long-term survival benefit of endovascular aortic intervention require further discussion and additional follow-up. We believe that the characterization of the role of endovascular therapy involves close risk-benefit analysis based on patient risk, disease presentation, native and pathological anatomy, and long-term outlook. Through review of the randomized prospective literature and relevant retrospective data, we explore the role of catheter-based solutions in abdominal and thoracic aortic disease, with a focus on aortic aneurysm and aortic dissection (AD). For patients with appropriate anatomy, endovascular aortic repair (EVAR) has largely supplanted open aortic repair (OAR) in the treatment of abdominal aortic aneurysm (AAA), both in the elective setting and during rupture. Similarly, thoracic endovascular aortic repair (TEVAR) has gained popularity in treating disease of the descending thoracic aorta, in both aneurysmal degeneration and AD. Similar adoption has been seen in treating other disease states, namely traumatic aortic injury. However, we recognize the current limitations of endovascular therapy and detail the innovations being pursued to advance endovascular therapy in the future.
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Patil et al. (2026) conducted a review in Aortic aneurysm, aortic dissection, and other aortic diseases. Endovascular aortic repair (EVAR) and thoracic endovascular aortic repair (TEVAR) vs. Open aortic repair (OAR) or medical therapy was evaluated. Endovascular aortic repair (EVAR and TEVAR) reduces perioperative mortality and morbidity compared to open repair in patients with suitable anatomy, though long-term durability requires surveillance.
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