This case demonstrates multimodal dermoscopy's effectiveness in evaluating atypical skin tumors, suggesting improved diagnostic accuracy.
An adult male agricultural worker presented with an asymptomatic, heterogeneously pigmented, indurated nodule featuring multiple protuberances on the left pelvic skin. Cross-polarized dermoscopy revealed pink structureless areas and a hyperpigmented reticular network; yellow light dermoscopy accentuated the pigmentary network and entangling vasculature. Ultraviolet-induced fluorescence dermoscopy demonstrated blue–white autofluorescence of surface keratin and milky-white fluorescence of the collagenous/myxoid stroma. Histopathology showed a monomorphic spindle-cell infiltrate without atypia; immunohistochemistry (IHC) confirmed a CD34-positive, S100-negative spindle-cell neoplasm consistent with a myxoid variant of dermatofibrosarcoma protuberans. This case highlights the diagnostic utility of multimodal dermoscopy integrated with histopathology and supportive IHC in precisely evaluating atypical cutaneous tumours.
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H et al. (2025) studied this question.
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