What question did this study set out to answer?

Investigate the relationship between educational attainment and cerebrovascular mortality rates across different demographics.

February 2, 2026Stroke

Abstract HUP18: Disparities in Stroke Mortality by Educational Attainment in the U.S.

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Key result

Higher education linked to up to ~91% lower cerebrovascular mortality versus high school graduates.

Why the study?

Education is linked to socioeconomic status and health outcomes, prompting an investigation into the association between educational attainment and age- and sex-stratified cerebrovascular mortality rates across the US.

Is educational attainment associated with cerebrovascular mortality rates in the U.S. population?

Population

Estimated 258.7 million US residents with 163,226 annual cerebrovascular deaths

Comparison

Educational attainment levels vs high school graduates

Design

Population-based cross-sectional mortality study

Authors

SGSedat GülCleveland Clinic MCMarek CiernyMedical College of Wisconsin NKNithin KurraCleveland Clinic

Discussion

Member takes

Implication

Education-related stroke mortality disparities warrant no practice change; leaves causal mechanisms and interventions open for prospective study.

Key Points

Investigate the relationship between educational attainment and cerebrovascular mortality rates across different demographics.
Analyzed cerebrovascular mortality rates by age, sex, and educational attainment from 2021 to 2023.
Utilized data from the Underlying Cause of Death database and the American Community Survey.
Calculated mortality rate ratios (MRR) comparing educational levels, using high school graduates as the referent.
Identified 163,226 cerebrovascular deaths among 258.7 million residents, with educational data available for 98.3%.
Observed a clear inverse relationship: higher educational attainment correlates with lower stroke mortality rates.
Men aged 35-44 with professional degrees had an MRR of 0.091 compared to high school graduates; women had an MRR of 0.122.
In those over 65, men had an MRR of 0.510, and women had an MRR of 0.363, indicating significant protection from stroke mortality with higher education.

Structured PICO

Is educational attainment associated with cerebrovascular mortality rates in the U.S. population?

Population

All U.S. residents (population estimate 258.7 million) from 2021 to 2023

Intervention

Higher educational attainment (e.g., graduate or professional degree)

Comparator

High school graduates

Outcome

Cerebrovascular mortality rate (annual deaths per 100,000 individuals)hard clinical

Lower educational attainment is significantly associated with higher stroke mortality across the lifespan in the U.S. population.

Cite This Study

Gül et al. (2026) studied this question. Individuals with higher educational attainment have significantly lower cerebrovascular mortality rates, with MRR of 0.091 for males and 0.122 for females aged 35-44 compared to high school graduates.

synapsesocial.com/papers/6980fc73c1c9540dea80e47a https://doi.org/10.1161/str.57.suppl_1.hup18

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Implication

Education-related stroke mortality disparities warrant no practice change; leaves causal mechanisms and interventions open for prospective study.

Abstract HUP18: Disparities in Stroke Mortality by Educational Attainment in the U.S.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Abstract HUP18: Disparities in Stroke Mortality by Educational Attainment in the U.S.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider