What question did this study set out to answer?

To explore the use of photocleavable protective groups in managing the activity of organic compounds and their potential as diagnostics and drugs.

February 2, 2026Journal of Materials Chemistry B0 citations

Photocleavable luminescent conjugates of 2-(2-aryl-5-(piperidin-1yl)-2H-1,2,3-triazol-4-yl)thiazoles and aminoacids, diagnostic and drugs

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TFTimur O. FominUral Federal University VKV. A. KrasilnikovUral Federal University ВШВадим А. ШевыринUral Federal University

Key Points

To explore the use of photocleavable protective groups in managing the activity of organic compounds and their potential as diagnostics and drugs.
Synthesis of luminescent conjugates with amino acids and photocleavable groups
Evaluation of the ability to mask and release functions of compounds
Assessment of biological activity on substrates
Demonstrated successful masking of toxic and biologically active compounds
Shown efficient release of compounds through light exposure
Found potential applications in diagnostics and drug delivery

Abstract

Photo-cleavable protective groups (PPGs) offer a straightforward method of temporarily masking the aggressive functions of organic compounds and inactivating biologically active or toxic substrates. They can then be released from...

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Cite This Study

Fomin et al. (2026) studied this question.

synapsesocial.com/papers/6980fcb6c1c9540dea80e833 https://doi.org/10.1039/d5tb02183a

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February 2, 2026Journal of Materials Chemistry B0 citations

Photocleavable luminescent conjugates of 2-(2-aryl-5-(piperidin-1yl)-2H-1,2,3-triazol-4-yl)thiazoles and aminoacids, diagnostic and drugs

View Full Paper

TFTimur O. FominUral Federal University VKV. A. KrasilnikovUral Federal University ВШВадим А. ШевыринUral Federal University

Key Points

To explore the use of photocleavable protective groups in managing the activity of organic compounds and their potential as diagnostics and drugs.
Synthesis of luminescent conjugates with amino acids and photocleavable groups
Evaluation of the ability to mask and release functions of compounds
Assessment of biological activity on substrates
Demonstrated successful masking of toxic and biologically active compounds
Shown efficient release of compounds through light exposure
Found potential applications in diagnostics and drug delivery

Abstract

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Cite This Study

Fomin et al. (2026) studied this question.

synapsesocial.com/papers/6980fcb6c1c9540dea80e833 https://doi.org/10.1039/d5tb02183a

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View Full Paper