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February 2, 2026Reproductive Biology and Endocrinology2 citationsOpen Access

Association of metal exposure in follicular fluid with assisted reproductive technology outcomes in East Chinese women

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YHYao HanZGZongwei GuoDYDi Yuan

Key Points

  • The research aims to explore how metal exposure in follicular fluid affects fertility outcomes in women undergoing assisted reproductive technology.
  • Analyzed the concentrations of metal elements in follicular fluid of women
  • Examined outcomes of assisted reproductive technology procedures
  • Proposed further investigation into biological mechanisms involved.
  • Found a correlation between metal exposure and fertility decline
  • Identified specific metal elements potentially harmful to fertility
  • Suggested the need for additional research to clarify underlying mechanisms.

Abstract

These findings underscore the critical importance of considering metal exposure in relation to female fertility. Furthermore, additional research is necessary to elucidate the biological mechanisms linking metal elements in FF to the decline in female fertility.

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Cite This Study

Han et al. (2026) studied this question.

synapsesocial.com/papers/6980fcd6c1c9540dea80e971https://doi.org/10.1186/s12958-026-01530-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serum trace and heavy metal exposure and IVF/ICSI outcomes: modifying effects of maternal diet in a prospective cohort2026
  2. 2Environmental exposure to lead and cadmium only minimally affects the redox system of the follicular fluid and the outcome of intracytoplasmic sperm injection2024 · 1 citations
  3. 3Associations between Non-Essential Trace Elements in Women’s Biofluids and IVF Outcomes in Euploid Single-Embryo Transfer Cycles2024 · 7 citations
  4. 4Exposure profiles of legacy and emerging per- and polyfluoroalkyl substances in follicular fluid and their impacts on assisted reproductive outcomes: A multicenter study in China2026
  5. 5Integrated chemical exposome–metabolome profiling of follicular fluid and associations with fertility outcomes during assisted reproduction2025