Azole exposure led to the development of fluconazole resistance in C. tropicalis BSI; hematologic malignancies, azole resistance, chronic obstructive pulmonary disease and having intravenous catheters increased mortality rate. The use of echinocandins or amphotericin B and catheter removal improved outcomes, underscoring the need for early resistance detection and targeted treatment.
Wang et al. (Thu,) studied this question.