Flexible steric bulk of sugar wingtip substituents on bis(N-heterocyclic carbene) ligands of diplatinum complexes via chair–twist-boat conformational changes

Key Points

• The research investigates how the steric properties of sugar substituents on bis(N-heterocyclic carbene) ligands influence the structure of diplatinum complexes.
• Synthesis of p-toluenethiolate-bridged diplatinum complex
• Characterization of conformations using molecular modeling
• Examination of acetyl-protected glucopyranosyl substituents
• Analysis of core geometry around platinum centers
• All sugar substituents adopt a chair conformation
• Conformational flexibility leads to an open structure around the Pt2S2 core
• Steric bulk affects the overall stability of the complex