What question did this study set out to answer?

The aim is to understand how apathy and depression impact cognitive decline and autonomy in neurodegenerative diseases.

Apathy and Depression Impact on Cognitive Decline: Neuropsychological Specificities across Neurodegenerative Diseases

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Cross-sectional study investigates cognitive decline in neurodegenerative diseases, suggesting apathy and depression affect outcomes significantly.

The aim is to understand how apathy and depression impact cognitive decline and autonomy in neurodegenerative diseases.
Conducted a cross-sectional study involving 53 patients with neurodegenerative diseases.
Performed neuropsychological testing alongside Geriatric Depression Scale and Starkstein’s Apathy Scale.
Assessed Activities of Daily Living (ADL) to evaluate autonomy.
56% of patients exhibited cardiovascular pathologies, 20% had Parkinson’s disease, and 22% had Mild Cognitive Impairment-Alzheimer Disease.
Findings showed that apathy predicted language initiative and negatively correlated with working memory and language.
Depression was found to predict autonomy when accounting for apathy.

Oliveri et al. (2025) studied this question.

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Cross-sectional study investigates cognitive decline in neurodegenerative diseases, suggesting apathy and depression affect outcomes significantly.