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February 2, 2026The European Physical Journal PlusOpen Access

Radiation risk mitigation in human space exploration: a primer, a vision, and the state of the art

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Authors

NLNarici LivioBGBaiocco GiorgioCGCenci Giovanni

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Overview

This comprehensive review demonstrates effective strategies to mitigate radiation risks in human space exploration, implying improved health outcomes for astronauts on long missions.

Key Points

  • The aim is to explore the health risks associated with space radiation and identify effective mitigation strategies.
  • Reviewed biological effects of galactic cosmic rays and solar particle events.
  • Analyzed current risk assessment and mitigation techniques, including shielding and pharmacological agents.
  • Evaluated experimental platforms and ongoing European research programs related to radiation.
  • Identified significant health risks from space radiation, including DNA damage and cardiovascular disease.
  • Highlighted the combined effects of radiation and microgravity on human health.
  • Proposed a structured framework for radiation risk mitigation in long-duration missions.

Cite This Study

Livio et al. (2026) studied this question.

synapsesocial.com/papers/6980fe48c1c9540dea810406https://doi.org/10.1140/epjp/s13360-025-07199-8
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Also Consider

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  2. 2Beyond Earthly Limits: Protection against Cosmic Radiation through Biological Response Pathways2024
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  4. 4Integrative focus on the space exposome-integrome: physiological challenges and practical limits of countermeasures beyond low Earth orbit2025
  5. 5Understanding Cancer Development Processes after HZE-Particle Exposure: Roles of ROS, DNA Damage Repair and Inflammation2015 · 124 citations