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February 2, 2026Open Access

T2D accounts for ~93% of DKA cases, primarily triggered by infections and non-compliance.

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Why the study?

Diabetic ketoacidosis is a life-threatening acute complication increasingly seen in type 2 diabetes, requiring prompt recognition of clinical features, precipitating factors, and timely management to reduce morbidity and mortality.

Population

83 in-patients diagnosed with DKA admitted to a tertiary care teaching hospital

Design

Cross-sectional study

Key result

Among 83 patients with diabetic ketoacidosis, type 2 diabetes was predominant (92.8%), with infections (73.4%) and non-compliance (66.2%) being the leading precipitating factors.

Authors

AGAjay GopinathAKArun Kumar KSSSuhas M S

Discussion

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Member takes

Overview

May inform local DKA prevention in type 2 diabetes; extends prior observations but leaves generalizability open.

Key Points

  • The study aims to evaluate clinical profiles, precipitating factors, and treatment patterns in patients with diabetic ketoacidosis.
  • Conducted as a cross-sectional study over six months in a tertiary care hospital.
  • Included 83 in-patients diagnosed with diabetic ketoacidosis based on inclusion criteria.
  • Data were collected through a case profile form documenting demographics, clinical presentations, and treatment patterns.
  • Descriptive statistics and percentage analysis were performed for data interpretation.
  • 56.6% of patients were male; prevalence of type 2 diabetes was 92.8%.
  • Common symptoms included nausea and vomiting (63.8%) and abdominal pain (43.3%).
  • Infections (73.4%) and non-compliance with treatment (66.2%) were the main precipitating factors.
  • All patients received subcutaneous insulin and intravenous normal saline; 85.5% were given intravenous insulin.
  • 56.6% of patients were discharged within five days of hospitalization.

Study Design

Type

Cross-Sectional (n=83)

Multicenter

No

Structured PICO

P
Population
83 in-patients diagnosed with diabetic ketoacidosis admitted to a tertiary care teaching hospital in India.
O
Outcome
Clinical profile, precipitating factors, and prescribing patterns

In this Indian tertiary care setting, DKA was predominantly seen in type 2 diabetes patients, with infections and non-compliance as major precipitating factors, and treatment aligned with standard guidelines.

Cite This Study

Gopinath et al. (2025) conducted a cross-sectional in Diabetic ketoacidosis (n=83). Diabetic ketoacidosis was evaluated on Clinical profile, precipitating factors, and prescribing patterns. Among 83 patients with diabetic ketoacidosis, type 2 diabetes was predominant (92.8%), with infections (73.4%) and non-compliance (66.2%) being the leading precipitating factors.

synapsesocial.com/papers/6980fe57c1c9540dea810642https://doi.org/10.5281/zenodo.18428681
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Profile, Precipitating Factors, and In-Hospital Outcomes of Patients with Diabetic Ketoacidosis: A Prospective Study from a Tertiary Care Center in North India2026
  2. 2Clinical Pattern, Precipitating Factors, and Outcome of Diabetic Ketoacidosis Patients Visiting Adult Emergency at Saint Paul’s Hospital Millennium Medical College2024 · 2 citations
  3. 3Precipitating factors, presentation and outcomes of diabetic ketoacidosis among patients seen at Moi Teaching and Referral Hospital (MTRH), Eldoret Kenya.2024 · 1 citations
  4. 42280-P: Diabetic Ketoacidosis: A Systematic Review of Precipitants, Treatment, and Outcomes with a Mortality Meta-Analysis2026
  5. 5Clinical characteristics and outcomes of care in patients hospitalized with diabetic ketoacidosis2022 · 24 citations