Key result
~40% of Fontan patients now reach adulthood but face complications like HF and arrhythmias.
Why the study?
Despite improved survival into adulthood, patients living with Fontan circulation struggle with complications including heart failure, arrhythmias, end-organ dysfunction, and premature death.
This review summarizes common complications, proposes a clinical and mortality risk score, and explores catheter interventions and transplant options for the growing population of patients with Fontan circulation.
Warrants close monitoring for HF and arrhythmias in adult Fontan survivors; leaves open prospective validation of proposed risk scores.
Since the first operation performed in 1968, the worldwide population of patients living with Fontan circulation is dramatically growing, with 40% reaching adulthood in the current era. Despite this remarkable improvement in survival, some patients struggle with Fontan-related complications including heart failure, arrhythmias, end-organ dysfunction, and premature death. This review aims at describing common complications of the Fontan circulation, proposing a clinical and mortality risk score to better stratify this complex population as well as exploring the current state of art in catheter interventions and transplant.
No takes yet. Share an insight, caveat, or question.
Barracano et al. (2025) conducted a review in Fontan circulation. This review describes common complications of the Fontan circulation, proposes a clinical and mortality risk score, and explores the current state of art in catheter interventions and transplant.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: