Biomimetic O-Demethylation at a Copper(II) Center with Imine Ligand: A Structural and Computational Study

Key Points

• The aim is to explore Cu(II)-mediated O-demethylation inspired by enzymes.
• Examined the structural properties of Cu(II) with imine ligands
• Conducted computational studies to model catalytic activity
• Investigated the mechanism of O-demethylation
• Demonstrated effective cleavage of C–O bonds
• Highlighted the role of imine ligands in enhancing catalytic activity
• Confirmed structural similarities to enzymatic processes