Abstract We report a 55-year-old female who presented with choreiform movements in the right upper and lower limbs and uncontrolled blood sugar levels. Magnetic resonance imaging (MRI) of the brain revealed hyperdense lesions, without diffusion restriction or blooming on gradient echo, in the left lentiform and caudate nuclei. The clinical presentation and MRI brain findings pointed towards a diagnosis of diabetic striatopathy (DS). DS, an underrecognized and underdiagnosed condition, primarily affects older women with poorly-managed diabetes mellitus. Effective management of this disorder chiefly depends on maintaining optimal blood glucose levels. After rigorous glycemic control using insulin therapy, the patient’s symptoms started to improve, achieving complete remission of symptoms in about a month.
Mangudkar et al. (2026) studied this question.