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February 2, 20260 citations

Clinical Parameters and Radiomics of Vestibular Schwannomas in NF2-related Schwannomatosis.

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NBNina BoeUniversität HamburgVMVictor-F MautnerRFReinhard E Friedrich

Key Points

  • The study aims to explore how imaging features relate to clinical outcomes in vestibular schwannomas associated with NF2.
  • Analyzed imaging features using radiomic profiling
  • Assessed the influence of tumor laterality
  • Examined the impact of patient age on clinical outcomes
  • Homogeneity in imaging features linked to aggressive growth in younger patients
  • Heterogeneity indicated tumor progression in older patients
  • Radiomic biomarkers may enhance traditional volumetric assessments

Abstract

Radiomic profiling indicates that both tumor laterality and patient age influence the relationship between imaging features and clinical outcomes in NF2-associated VS. Homogeneity was linked to aggressive growth in younger patients, heterogeneity characterized progression in older patients. These findings suggest that radiomic biomarkers may complement volumetric measures and support individualized monitoring and treatment strategies in NF2.

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Cite This Study

Boe et al. (2026) studied this question.

synapsesocial.com/papers/6980feabc1c9540dea810f1chttps://doi.org/10.21873/anticanres.17992
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1High-Dimensional Imaging of Vestibular Schwannoma Reveals Distinctive Immunological Networks Across Histomorphic Niches in<i>NF2</i>-related Schwannomatosis2024 · 2 citations
  2. 2Nodular Growths of NF2-Related Schwannomatosis Vestibular Schwannoma: Clinical and Therapeutical Consequences2025
  3. 3[Molecular Pathogenesis, Genetic Profiles, and Therapeutic Strategies for NF2-Related Schwannomatosis].2025
  4. 4Management strategies for vestibular schwannomas in patients with NF2-related schwannomatosis: a systematic review2026
  5. 5Analysis of tumor microenvironment composition in vestibular schwannomas: insights into NF2-associated and sporadic variations and their clinical correlations2024 · 1 citations