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This study assesses potential adjuvant agents to enhance fat graft viability in reconstructive surgery.

An Evidence-Based Assessment of Adjuvant Therapy in Autologous Fat Transfer

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This study assesses potential adjuvant agents to enhance fat graft viability in reconstructive surgery.
Conducted a targeted literature review with a weighted scoring analysis.
Evaluated agents based on FDA approval, effectiveness, safety, and cost-effectiveness.
Scoring framework included six key domains rated on a scale from 1 to 5.
Deferoxamine scored highest (22/28), showing significant ability to promote angiogenesis.
Insulin with β-fibroblast growth factor scored 18 but lacks FDA approval.
Hyaluronan hydrogel and poloxamers scored 17 and 16, respectively, indicating potential effectiveness.

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A targeted literature review ranks adjuvant agents to improve fat graft viability, indicating deferoxamine as a promising candidate.

Sarpong et al. (2026) studied this question.

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