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To investigate a rare autoimmune blistering disorder in a young female and its potential triggers and treatments.

A Widespread Pruritic Blistering Eruption in a Young Female

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To investigate a rare autoimmune blistering disorder in a young female and its potential triggers and treatments.
Clinical examination of blistering eruption on trunk and upper limbs
Laboratory studies to assess inflammatory markers and eosinophilia
Serological testing for antibodies against BP180
Histopathological examination for blister characterization
Direct immunofluorescence for immunoglobulin deposition
Patient exhibited multiple tense bullae with raised inflammatory markers
Laboratory tests indicated marked eosinophilia
High-titre antibodies against NC16A domain of BP180 were found
Histopathology showed subepidermal blisters with eosinophil-rich infiltrate
Patient achieved sustained remission with rituximab treatment

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A case illustrates an autoimmune blistering disorder triggered by viral infection and ibuprofen exposure, revealing implication for treatment.

Attard et al. (2026) studied this question.

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A case illustrates an autoimmune blistering disorder triggered by viral infection and ibuprofen exposure, revealing implication for treatment.