These guidelines provide a clear and practical framework for the effective implementation of digital pathology (DP) in routine anatomical pathology practice. Digital pathology, defined as the digitization of microscope slide into high-resolution whole slide images, is transforming the diagnostic workflow by enabling remote access, improved image analysis, integration with artificial intelligence (AI), and enhanced data management. While digital systems are becoming increasingly integrated into pathology laboratories, the physical archiving of microscope slides remains a legal and procedural requirement in many countries, particularly for histological and cytological materials. As DP continues to evolve globally, the establishment of clear standards, technical requirements, validation procedures, and interoperability guidelines is essential to maintain diagnostic accuracy, patient safety, and system reliability. These recommendations address key technical, organizational, and legal aspects of DP implementation, with an emphasis on ensuring consistent quality and minimizing variability in diagnostic outcomes. The outlined approach supports the safe and effective adoption of DP as an integral element of modern digital healthcare.
Szylberg et al. (2026) studied this question.