Risk factors and predicted model for clinical relapse after antiviral therapy cessation in chronic hepatitis B patients: a retrospective real-world data analysis

Key Points

• To identify risk factors and develop a predictive model for relapse after stopping antiviral therapy in chronic hepatitis B patients.
• Conducted a retrospective analysis of data from chronic hepatitis B patients post-antiviral therapy cessation.
• Evaluated factors such as age, HBV DNA load, HBsAg levels, and antiviral treatment duration.
• Developed a predictive model based on identified risk factors.
• Age, HBV DNA load, HBsAg quantification, and total antiviral duration significantly influence relapse.
• The predictive model showed strong clinical predictive value for assessing relapse risk.