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This study aims to explore the phylogenetic relationships and evolutionary history of two mosquito species using complete mitochondrial genomes.

February 2, 2026Animal Cells and SystemsOpen Access

Evolutionary insights from complete mitochondrial genomes of Aedes albopictus and Culex pipiens molestus (Diptera: Culicidae)

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Comparative analysis uncovers evolutionary relationships in mosquito vectors, suggesting implications for vector biology.

This study aims to explore the phylogenetic relationships and evolutionary history of two mosquito species using complete mitochondrial genomes.
Conducted a comparative mitogenomic analysis with 20 mosquito species.
Sequenced mitochondrial genomes comprising protein-coding genes, tRNAs, and rRNAs.
Used maximum likelihood and Bayesian methods for phylogenetic inference.
Analyzed lineage-specific patterns in codon usage and base composition.
Established robust phylogenetic relationships resolving genus-level classifications.
Identified a deep divergence between Anopheles and the Aedes–Culex clade around 51.8 million years ago.
Determined distinct evolutionary divergence times with Ae. albopictus diverging at 11.7 million years and Cx. p. molestus at 2.35 million years.

Akintola et al. (2026) studied this question.

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