What question did this study set out to answer?

The study aimed to evaluate the effectiveness of a single 400 mg dose of albendazole against soil-transmitted helminths in children and assess socio-demographic influences on treatment outcomes.

February 2, 2026The Indian Journal of Medical ResearchOpen Access

Effectiveness of single-dose albendazole against soil-transmitted helminth infection in children: A longitudinal study in a tribal dominated district of Odisha, India

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The study aimed to evaluate the effectiveness of a single 400 mg dose of albendazole against soil-transmitted helminths in children and assess socio-demographic influences on treatment outcomes.
Longitudinal study with 1246 children aged 1-15 years from 18 clusters.
203 STH-positive children treated with albendazole and monitored for stool samples at Days 14, 28, and 42.
Egg counts measured using the Kato-Katz method.
Cure rates and egg reduction rates calculated and analyzed with repeated measures ANOVA.
Albendazole achieved an egg reduction rate of 96.2% for Ascaris lumbricoides and 93.8% for Ancylostoma duodenale.
Cure rates were 66.7% for A. lumbricoides and 52.94% for A. duodenale, below WHO thresholds.
Gender and geography influenced initial egg counts, with higher burdens in females and children from Nabarangpur.
Egg reduction was consistent across schooling and tribal groups.

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Implication

Longitudinal study demonstrates albendazole's effectiveness against soil-transmitted helminths in children, suggesting further interventions may be necessary.

Cite This Study

Sethi et al. (2026) studied this question.

synapsesocial.com/papers/6980fff5c1c9540dea812ec4 https://doi.org/10.25259/ijmr_820_2025

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Implication

Longitudinal study demonstrates albendazole's effectiveness against soil-transmitted helminths in children, suggesting further interventions may be necessary.

Effectiveness of single-dose albendazole against soil-transmitted helminth infection in children: A longitudinal study in a tribal dominated district of Odisha, India

Key Points

Discussion

Implication

Cite This Study

Effectiveness of single-dose albendazole against soil-transmitted helminth infection in children: A longitudinal study in a tribal dominated district of Odisha, India

Key Points

Discussion

Implication

Cite This Study

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