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February 2, 2026ChemPhotoChem5 citations

Electron Donor–Acceptor (EDA) Complexation With Hypervalent Iodines: An Update

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DLDipti LaiSGSumit GhoshSSSubrata Sinha

Key Points

  • The aim is to review recent developments in EDA complexation using hypervalent iodine compounds for organic synthesis.
  • Review of literature up to June 2025
  • Analysis of synthetic strategies with EDA complexes
  • Integration of hypervalent iodine in reactions
  • Highlighting the efficiency of catalyst-free transformations
  • Emphasizing low toxicity and environmental benefits
  • Identifying novel uses of hypervalent iodine as electron acceptors

Abstract

Electron donor–acceptor (EDA) complexes have gained prominence for enabling efficient, catalyst‐free transformations under mild conditions. On the other hand, hypervalent iodine compounds, known for their low toxicity, environmental compatibility, and versatile oxidative reactivity, have recently emerged as powerful electron acceptors in EDA complexation. Therefore, the integration of these concepts will offer a new route for sustainable, selective, and innovative strategies in modern organic synthesis. This review summarizes the recent advances on the synthetic strategies occurred through EDA complex formation using hypervalent iodine reagent (HIR) with literature coverage up to June, 2025.

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Cite This Study

Lai et al. (2026) studied this question.

synapsesocial.com/papers/69810013c1c9540dea813314https://doi.org/10.1002/cptc.202500258
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