July 30, 2015Circulation
Extracranial Systemic Embolic Events in Patients With Nonvalvular Atrial Fibrillation
Key result
Extracranial SEEs comprise a substantial share of AF thromboembolism and carry ~25% 30-day mortality.
- or 11.5
Why the study?
What is the incidence, clinical characteristics, and mortality associated with extracranial systemic embolic events in patients with nonvalvular atrial fibrillation?
Population
37,973 participants with nonvalvular atrial fibrillation from 4 large contemporary randomized clinical…
Design
Cohort
Follow-up
91,746 patient-years
Authors
Discussion
Loading...
Member takes
Implication
SEE confer high short-term mortality in AF; extends thromboembolic characterization beyond stroke yet leaves optimal prevention unresolved.
Structured PICO
What is the incidence, clinical characteristics, and mortality associated with extracranial systemic embolic events in patients with nonvalvular atrial fibrillation?
P
Population
37,973 participants with nonvalvular atrial fibrillation from 4 large contemporary randomized clinical trials of anticoagulation
O
Outcome
Incidence, characteristics, and outcomes (morbidity and mortality) of extracranial systemic embolic events (SEEs)hard clinical
Extracranial systemic embolic events account for 11.5% of clinically recognized thromboembolic events in nonvalvular atrial fibrillation and carry a high mortality risk comparable to ischemic stroke.
Cite This Study
Bekwelem et al. (2015) studied this question. Extracranial systemic embolic events (SEEs) accounted for 11.5% of thromboembolic events in atrial fibrillation, with a 30-day mortality rate of 25%.