⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

February 1, 2026European journal of medical researchOpen Access

Liraglutide alleviates sepsis-associated encephalopathy via attenuating neuronal damage, glial cell activation and mitochondrial dysfunction in a mouse model of sepsis

Xiaoming Li Jun Wang Rongji Zhang Haoran He Linjue Wang Yuliang Wang Hongyu Yi

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to investigate the neuroprotective effects of liraglutide on sepsis-associated encephalopathy (SAE).
Utilized a mouse model of sepsis to evaluate liraglutide's effects
Assessed neuronal damage, glial cell activation, and mitochondrial function
Conducted comparative analyses between treated and untreated groups
Liraglutide reduced neuronal damage observed in sepsis models
Glial cell activation was significantly attenuated in treated mice
Improvements in mitochondrial function were noted, correlating with enhanced neuroprotection

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Liraglutide improves neuroprotection from sepsis-associated encephalopathy in mice, suggesting a potential therapeutic role.

Abstract

GLP-1R agonist Liraglutide may have neuroprotective properties on SAE.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69843398f1d9ada3c1fb0dca https://doi.org/10.1186/s40001-026-03974-0

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Liraglutide alleviates sepsis-induced encephalopathy via attenuating neuronal damage, glial cell activation and mitochondrial dysfunction in a mouse model of sepsis2025
2Liraglutide protects against microvascular dysfunction and sepsis-mediated inflammation and organ injury2024 · 1 citations
3GLP-1RA Liraglutide Attenuates Sepsis by Modulating Gut Microbiota and Associated MetabolitesOriginal Research · 2026 · 2 citations
4Liraglutide Attenuates Disease Severity in Experimental Autoimmune Encephalomyelitis by Modulating Splenic T Helper Cell Subsets2025
5Glutathione attenuates sepsis-associated encephalopathy via dual modulation of NF-κB and PKA/CREB pathways.2025