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February 5, 2026European journal of medical research0 citationsOpen Access

Inflammation meets insulin resistance: the role of the CRP-triglyceride-glucose index in association with frailty among middle-aged and older adults in China

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WYWei YanJZJing ZhaoQHQianyi Hao

Key Points

  • The research aims to investigate the link between the CRP-triglyceride-glucose index and frailty in middle-aged and older adults.
  • Analyzed data from a population-representative cohort.
  • Assessed the association between the CRP-triglyceride-glucose index and frailty.
  • Considered factors like age and inflammation levels.
  • Found a significant, independent association between the CTI and frailty.
  • Indicated that CTI could help with risk stratification in aging individuals.
  • Emphasized the need for longitudinal studies to confirm prognostic value.

Abstract

CTI is independently associated with frailty in a population-representative cohort. Therefore, CTI-based approaches may facilitate risk stratification in aging populations, while longitudinal validation is warranted to establish prognostic value.

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Cite This Study

Yan et al. (2026) studied this question.

synapsesocial.com/papers/698433a5f1d9ada3c1fb0ef8https://doi.org/10.1186/s40001-026-03951-7
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