Recent advances in the synthesis of α-dystroglycan O -mannose glycans

Yue Yang; Huiran Hao; Hebin Shao; Jinhua Zhang; Weilu Tian; Heng Zhang; Beibei Liu; Fei Liu; Peixue Ling

doi:10.1039/d5ra10119k

January 1, 2026RSC AdvancesOpen Access

Recent advances in the synthesis of α-dystroglycan O -mannose glycans

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Key Points

This review explores the latest methods for synthesizing O-mannose glycans associated with α-dystroglycan.
Analysis of chemical strategies for glycan synthesis
Evaluation of enzymatic methods
Review of chemoenzymatic techniques
Identified three major O-mannose glycans
Discussed the advantages of different synthesis methods

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Implication

This review analyzes synthesis strategies for O-mannose glycans, highlighting their importance in glycobiology.

Abstract

This review provides a comprehensive analysis of the chemical, enzymatic, and chemoenzymatic strategies for synthesizing the three major O -mannose glycans.

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Yang et al. (2026) studied this question.

synapsesocial.com/papers/698433e9f1d9ada3c1fb168c https://doi.org/10.1039/d5ra10119k

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Recent advances in the synthesis of α-dystroglycan O -mannose glycans

Key Points

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Implication

Abstract

Discussion

Cite This Study

Recent advances in the synthesis of α-dystroglycan O -mannose glycans

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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