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February 5, 2026Malaria JournalOpen Access

Pooled prevalence of Glucose-6-phosphate dehydrogenase deficiency among malaria patients in Ethiopia: a systematic review and meta-analysis

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The aim is to determine the pooled prevalence of glucose-6-phosphate dehydrogenase deficiency among malaria patients in Ethiopia.
Conducted a systematic review and meta-analysis of existing studies on G6PD deficiency in malaria patients.
Analyzed data to determine prevalence rates and genetic variants associated with G6PD deficiency.
The overall pooled prevalence of G6PD deficiency was found to be 6%.
Emerging mutant variants, including ChrX:154535443, ChrX:6369, and ChrX:6504, were identified.
A376G and A376T mutant variants were most commonly associated with G6PD deficiency cases.

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Systematic review reports the prevalence of G6PD deficiency in malaria patients, suggesting genetic variants are significant.

Dessie et al. (2026) studied this question.

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