This report demonstrates hydrodifluoromethylation of unactivated alkenes, indicating a new approach for synthetic chemistry.
Herein, we report a photocatalyst-and metal-free, visible-light-induced hydrodifluoromethylation of unactivated alkenes via an acetamide-mediated activation of difluoromethyl aryl sulfones, a class of bench-stable CF₂H reagents. The cooperative roles of acetamide,...
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Lou et al. (2026) studied this question.
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