The aim is to explore liposomal delivery of DNA aptamers to combat antibiotic resistance in bacteria.
Developing liposomes for DNA aptamer delivery
Testing aptamer efficacy against erythromycin methyltransferase
Assessing changes in antibiotic sensitivity in resistant S. aureus
Liposomal DNA aptamers effectively inhibit erythromycin methyltransferase
Erythromycin sensitivity is restored in resistant S. aureus
The approach shows potential for treating multidrug-resistant infections
Abstract
Liposomal delivery of Erm-inhibiting DNA aptamers restores erythromycin sensitivity in resistant S. aureus , providing a promising strategy to combat multidrug-resistant bacterial infections.
Administration de systèmes liposomaux d'aptamères d'ADN pour inhiber la résistance aux antibiotiques médie par la méthyltransférase de l'érythromycine | Synapse