Key result
Y-Check adolescent screening achieves appropriate care or referral for ~71% of youths with identified issues.
Why the study?
Evidence on the feasibility, acceptability, and effectiveness of contextually relevant comprehensive routine adolescent health check-ups in low- and middle-income settings is limited.
Does the Y-Check comprehensive health check-up intervention improve appropriate care and/or referral(s) in 10-19-year-old adolescents?
Observational (n=2,097)
Yes
Does the Y-Check comprehensive health check-up intervention improve appropriate care and/or referral(s) in 10-19-year-old adolescents?
The Y-Check comprehensive health check-up intervention was feasible, acceptable, and successfully linked adolescents to appropriate care and services in Zimbabwe.
Supports feasibility of adolescent screening in low-resource settings; leaves open whether RCTs would confirm effectiveness and guide scale-up.
Routine adolescent health check-ups can support healthy development and well-being, but evidence on the feasibility, acceptability and effectiveness of contextually relevant comprehensive check-ups in low- and middle-income settings is limited. We conducted a hybrid implementation-effectiveness study incorporating a mixed-methods pre−post design of Y-Check, a comprehensive health check-up intervention in Zimbabwe, as part of a multicountry study developed and coordinated by the World Health Organization. Eligible participants were 10–19-year-old adolescents attending school or community venues. We used self-administered digital questionnaires, provider-led clinical tests and nurse reviews to screen for 25 conditions/behaviors. We provided health promotion, on-site care and referral to relevant providers. From October 2022 to September 2023, 2,097 adolescents were enrolled, of whom 1,843 (87.9%) were seen at 6 months. The primary outcome of appropriate care and/or referral(s) for all identified issues was achieved for 70.8% (95% confidence interval: 68.7–72.9%) of 1,865 participants with at least one issue. At follow-up, there were improvements in nutrition, health-related quality of life, self-esteem, behaviors and educational outcomes. The intervention was feasible and largely acceptable. Uptake of referral services varied by issue. Y-Check cost US$47 per participant. Through Y-Check, we identified untreated conditions and risk behaviors and successfully treated and linked adolescents to services. Here we provide evidence on the potential of the intervention to positively impact health and well-being.
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Doyle et al. (2026) conducted an observational in Adolescent health (n=2,097). Y-Check comprehensive adolescent health check-up was evaluated on Appropriate care and/or referral(s) for all identified issues (95% CI 68.7-72.9). The Y-Check comprehensive adolescent health check-up intervention achieved appropriate care and/or referral for 70.8% of participants with at least one identified health issue.
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