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Multigene DNA methylation assay shows high specificity and sensitivity for triaging HPV-positive ASC-US women, suggesting a safer screening approach.
The host multigene DNA methylation assay demonstrates high specificity and good sensitivity for triaging HPV-positive ASC-US women, with the potential to reduce colposcopy referrals while maintaining robust detection of high-grade lesions, particularly in those aged ≥30 years.
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Xia et al. (2026) studied this question.
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